Non-specific immunity of BCG vaccine: A perspective of BCG immunotherapy
نویسندگان
چکیده
منابع مشابه
Improvement of Thermal Stability of BCG Vaccine
Background: Thermal stability (TS) is a part of the BCG vaccine characterization by which the consistency of process in BCG vaccine production could be confirmed. To enhance the TS of the vaccine, some prevalent stabilizers in different concentrations were added to the final formulation of BCG bulk prior to Freeze-drying process. We found a formulation more effective than the current stabilizer...
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Correspondence Non-specific effects of BCG? To the Editor—We would like to comment on the data presented by Aaby et al regarding their randomized trial of BCG in low-birth-weight children [1]. The authors designed their trial to test the hypothesis that among low-birth-weight infants, BCG vaccination at birth would reduce infant mortality by 25% compared with infants vaccinated later (on averag...
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BCG vaccines are the oldest vaccines in use today, but the protective effect of the vaccination is still controversial. The risk of contracting tuberculosis is low compared with the possible complications after this vaccination. In Austria the formerly used BCG vaccine was not available in the required amount and another vaccine was released by the drug authorities. This product, with a more vi...
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Tuberculosis (TB) is still responsible for 2 million deaths every year despite being a treatable airborne infectious disease. "Consumption" and "Phthisis" were terms historically used to describe TB, which was responsible for one in four deaths in the 19th century. Due to its infectious nature, chronic progression and long treatment, TB is a great burden for society. Moreover the emergence of m...
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Tuberculosis (TB) is one of the most important public health problems in the world and has been declared as a global emergency by the World Health Organization (WHO) in 1993. Bacillus Calmette-Guérin (BCG) is one of the first developed vaccines to prevent TB. Unfortunately, BCG vaccine has had a limited duration of protection and has shown controversial and variable levels of efficacy, especial...
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ژورنال
عنوان ژورنال: Trials in Vaccinology
سال: 2014
ISSN: 1879-4378
DOI: 10.1016/j.trivac.2014.08.002